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1

Fluorescent Epibatidine Agonists for Neuronal and Muscle-Type Nicotinic Acetylcholine Receptors

Jörg Grandl, Elias Sakr, Florence Kotzyba-Hibert, Florian Krieger, Sonia Bertrand, Daniel Bertrand, Horst Vogel, Maurice Goeldner, Ruud Hovius

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 134 KB

english, 2007

2

Pore region of TRPV3 ion channel is specifically required for heat activation

Grandl, Jörg, Hu, Hongzhen, Bandell, Michael, Bursulaya, Badry, Schmidt, Manuela, Petrus, Matt, Patapoutian, Ardem

Journal:

Nature Neuroscience

Year:

2008

Language:

english

File:

PDF, 729 KB

english, 2008

3

Fluorescent Epibatidine Agonists for Neuronal and Muscle-Type Nicotinic Acetylcholine Receptors

Jörg Grandl, Elias Sakr, Florence Kotzyba-Hibert, Florian Krieger, Sonia Bertrand, Daniel Bertrand, Horst Vogel, Maurice Goeldner, Ruud Hovius

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 134 KB

english, 2007

4

Functional asymmetry of transmembrane segments in nicotinic acetylcholine receptors

Jörg Grandl, Christophe Danelon, Ruud Hovius, Horst Vogel

Journal:

European Biophysics Journal

Year:

2006

Language:

english

File:

PDF, 360 KB

english, 2006

5

Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain

Grandl, Jörg, Kim, Sung Eun, Uzzell, Valerie, Bursulaya, Badry, Petrus, Matt, Bandell, Michael, Patapoutian, Ardem

Journal:

Nature Neuroscience

Year:

2010

Language:

english

File:

PDF, 758 KB

english, 2010

6

Modulation of proton-induced current fluctuations in the human nicotinic acetylcholine receptor channel

Christophe Danelon, Jörg Grandl, Ruud Hovius, Horst Vogel

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 1.58 MB

english, 2007

7

Piezo proteins are pore-forming subunits of mechanically activated channels

Coste, Bertrand, Xiao, Bailong, Santos, Jose S., Syeda, Ruhma, Grandl, Jörg, Spencer, Kathryn S., Kim, Sung Eun, Schmidt, Manuela, Mathur, Jayanti, Dubin, Adrienne E., Montal, Mauricio, Patapoutian, A

Journal:

Year:

2012

Language:

english

File:

PDF, 883 KB

english, 2012

8

Probing Mechanisms of Temperature Sensitivity of Thermo-TRPs

Patapoutian, Ardem, Grandl, Jörg

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

9

Outer Pore Domain of TRPV1 Ion Channel is Required for Temperature-Independent Step During Temperature-Activation

Grandl, Jorg, Kim, Sung Eun, Uzzell, Valerie, Bursulaya, Badry, Petrus, Matt, Bandell, Michael, Patapoutian, Ardem

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 63 KB

english, 2010

10

Single-Point Mutations in Ankyrin Repeat Six Make Mouse TRPA1 Sensitive to Hot Temperatures

Jabba, Sairam V., Goyal, Raman, Moldenhauer, Hans, Kalmeta, Breanna, Bandell, Michael, Latorre, Ramon, Patapoutian, Ardem, Grandl, Jorg

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

11

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

Jabba, Sairam, Goyal, Raman, Sosa-Pagán, Jason O., Moldenhauer, Hans, Wu, Jason, Kalmeta, Breanna, Bandell, Michael, Latorre, Ramon, Patapoutian, Ardem, Grandl, Jörg

Journal:

Year:

2014

Language:

english

File:

PDF, 2.87 MB

english, 2014

12

Balboa Binds to Pickpocket In Vivo and Is Required for Mechanical Nociception in Drosophila Larvae

Mauthner, Stephanie E., Hwang, Richard Y., Lewis, Amanda H., Xiao, Qi, Tsubouchi, Asako, Wang, Yu, Honjo, Ken, Skene, J.H. Pate, Grandl, Jörg, Tracey, W. Daniel

Journal:

Current Biology

Year:

2014

Language:

english

File:

PDF, 2.01 MB

english, 2014

13

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

Lee, Whasil, Leddy, Holly A., Chen, Yong, Lee, Suk Hee, Zelenski, Nicole A., McNulty, Amy L., Wu, Jason, Beicker, Kellie N., Coles, Jeffrey, Zauscher, Stefan, Grandl, Jörg, Sachs, Frederick, Guilak, F

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

14

The Pore-Domain of TRPA1 Mediates the Inhibitory Effect of the Antagonist 6-Methyl-5-(2-(Trifluoromethyl)Phenyl)-1H-Indazole

Moldenhauer, Hans, Latorre, Ramon, Grandl, Jorg

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

15

Localized force application reveals mechanically sensitive domains of Piezo1

Wu, Jason, Goyal, Raman, Grandl, Jörg

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.86 MB

english, 2016

16

channels

Coste, Bertrand, Xiao, Bailong, Santos, Jose S, Syeda, Ruhma, Grandl, Jörg, Spencer, S, Kim, Sung Eun, Schmidt, Manuela, Mathur, Jayanti, Dubin, Adrienne E, Montal, Mauricio, Patapoutian, Ardem

Year:

2012

Language:

english

File:

PDF, 1.59 MB

english, 2012

17

The Mechanism of Activation of Piezo Ion Channels

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 56 KB

english, 2017

18

Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization

Dubin, Adrienne E., Murthy, Swetha, Lewis, Amanda H., Brosse, Lucie, Cahalan, Stuart M., Grandl, Jörg, Coste, Bertrand, Patapoutian, Ardem

Journal:

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

19

Editorial Note to: Endogenous Piezo1 Can Confound Mechanically Activated Channel Identification and Characterization

Dubin, Adrienne E., Murthy, Swetha, Lewis, Amanda H., Brosse, Lucie, Cahalan, Stuart M., Grandl, Jörg, Coste, Bertrand, Patapoutian, Ardem

Journal:

Year:

2017

Language:

english

File:

PDF, 101 KB

english, 2017

20

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels

Lewis, Amanda H., Cui, Alisa F., McDonald, Malcolm F., Grandl, Jörg

Journal:

Year:

2017

Language:

english

File:

PDF, 2.65 MB

english, 2017

21

TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity

Sosa-Pagán, Jason O., Iversen, Edwin S., Grandl, Jörg

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.17 MB

english, 2017

22

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

Wu, Jason, Young, Michael, Lewis, Amanda H., Martfeld, Ashley N., Kalmeta, Breanna, Grandl, Jörg

Journal:

Year:

2017

Language:

english

File:

PDF, 9.99 MB

english, 2017

23

A cellular mechanism for age-induced itch

Lewis, Amanda H., Grandl, Jörg

Journal:

Year:

2018

Language:

english

File:

PDF, 238 KB

english, 2018

24

Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations

Kim, Sung Eun, Patapoutian, Ardem, Grandl, Jörg, Simon, Sidney Arthur

Journal:

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013